Loxonin S 12 tablets [Self-medication tax credit product].

Guideline for product delivery

Please note that this product takes approximately 1 week to 10 days from order to dispatch.

Products.

Loxonin S is an antipyretic analgesic characterised by rapid action and excellent efficacy.

● Contains antipyretic and analgesic ingredients with fast-acting characteristics for pain.
The antipyretic analgesic ingredient [loxoprofen sodium hydrate] quickly suppresses the substances that cause pain and fever (prostaglandins) and exerts excellent analgesic and antifebrile effects.
● Prodrug formulation with low gastric burden*.
Body-friendly prodrug formulation reduces the burden on the stomach.
*Prodrug preparations are those in which the ingredients are absorbed by the body and then transformed into the active form to exert their effects.
● Does not contain ingredients that make you sleepy (sedative-hypnotic ingredients).
● One tablet at a time works well.
● Small tablets that are easy to swallow.

Medicines can lead to serious health problems if the dosage and administration is deviated from.
Always read the product instructions carefully before use and follow the dosage and administration.
Side effects may occur even if dosage and administration are observed and used correctly. If you notice any abnormalities, discontinue use immediately and consult your doctor or pharmacist.

Usage notes.

■■ What not to do ■■
(Failure to comply may worsen current symptoms or increase the likelihood of side effects.)
1. should not be taken by the following persons
(1) People who have experienced allergic reactions to this product or any of its ingredients.
(2) People who have experienced asthma after taking this or other antipyretic analgesics or cold medicines.
(3) Children under 15 years of age.
(4) People undergoing the following treatments in a medical institution
Gastric and duodenal ulcers, liver disease, kidney disease, heart disease
(5) People whose doctor has indicated blood abnormalities (blood diseases) such as low red blood cell count (anaemia), low platelet count (difficulty in stopping bleeding or bleeding easily) or low white blood cell count.
(6) Pregnant women within 12 weeks of expected delivery date.
2.Do not take any of the following medicines while taking this medicine
Other antipyretic analgesics, cold and sedative medicines
3. Do not drink alcohol before and after taking the drug.
4. do not take continuously for a long time. (If symptoms such as pain persist after 3~5 days of taking
If returned, stop taking and seek medical attention).

■■Consulting ■■.
1.Consult a doctor, dentist or pharmacist before taking the following.
(1) Persons under the care of a doctor or dentist.
(2) Pregnant women or those thought to be pregnant.
(3) Lactating mothers.
(4) Older people.
(5) People who have had allergic reactions to medicines or other substances.
(6) Persons with the following diagnoses.
Bronchial asthma, ulcerative colitis, Crohn's disease, systemic lupus erythematosus, mixed connective tissue disease
(7) People who have had any of the following diseases.
Gastric and duodenal ulcers, liver disease, kidney disease, blood diseases
2.If you experience any of the following symptoms after taking the medicine, stop taking it immediately and consult your doctor, dentist or pharmacist with this document, as side effects may occur.
(1) If symptoms such as excessive drop in body temperature, collapse (lack of strength) or cooling of the extremities (cold limbs) are observed after taking antipyretic analgesics such as this medicine.
(2) If peptic ulcer or swelling appears after taking the drug.
In rare cases, gastrointestinal haemorrhage (vomiting blood, nausea, vomiting, abdominal pain, black tarry stools, bloody stools, etc.), perforation of the gastrointestinal tract (a hole in the gastrointestinal tract. Severe symptoms of nausea, vomiting, severe abdominal pain, etc.), narrowing or obstruction of the small or large intestine (nausea, vomiting, abdominal pain, bloating, etc.) may occur. In such cases, seek medical attention immediately.
(3) If any of the following symptoms occur after taking the drug
Relevant areas/symptoms.
Skin - Rash/redness, itching.
Gastrointestinal - abdominal pain, stomach discomfort, loss of appetite, nausea and vomiting, abdominal distension, heartburn, mouth ulcers, indigestion.
Cardiovascular - increased blood pressure, palpitations.
Psychoneurological system - drowsiness, numbness, dizziness, headache.
Other - chest pain, fatigue, facial hot flushes, fever, anaemia, haematuria.

In rare cases, the following serious symptoms may occur
If this happens, seek medical attention immediately.

Name of symptoms ... Symptoms.
Shock (anaphylaxis) - Skin itching, hives, hoarse voice, sneezing, itchy throat, breathlessness, palpitations and clouded consciousness soon after taking the drug.

Blood disorders - sore throat, fever, general lethargy, whiteness of the face and the back of the eyelids, easy bleeding (bleeding gums, nose bleeds, etc.), blue bruising (the colour does not disappear when pressed), etc.

Cutaneous Mucosal Eye Syndrome (Stevens-Johnson syndrome),
Toxic epidermal necrolysis, erythema multiforme, acute generalised eruptive pustulosis - High fever, red eyes, eye discharge, sores on the lips, sore throat, widespread skin rash/redness, blisters appearing on red areas of the skin, small patches (vesicles) on the reddened skin, general lethargy, loss of appetite, etc. may persist, Sudden worsening of the disease.

Renal impairment - fever, rash, decreased urine output, generalised swelling, generalised lethargy, joint pain (aching knots) and diarrhoea may occur.

Congestive heart failure - general lethargy, palpitations, shortness of breath, chest discomfort, chest pain, dizziness, fainting, etc.

Interstitial pneumonia - Shortness of breath or breathlessness when climbing stairs or exerting oneself a little, dry cough, fever, etc., which may appear suddenly or persist.

Liver dysfunction - fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes),
Brown urine, general lethargy and loss of appetite may occur.

Rhabdomyolysis - Muscle pain in limbs, shoulders, back, etc., numbness in limbs, weakness, stiffness, general lethargy, reddish-brown urine, etc.

Aseptic meningitis - Severe headache with neck tightness, fever, nausea and vomiting. (These symptoms have been reported more frequently, especially in people being treated for systemic lupus erythematosus or mixed connective tissue disease.)

Asthma - wheezing, hissing or breathlessness when breathing.

3.If any of the following symptoms persist or increase after taking the medicine, stop taking it and consult a doctor or pharmacist with this document.
Dry mouth, constipation, diarrhoea

4. If symptoms do not improve after 1~2 doses (possibly due to other diseases), stop taking and consult a doctor, dentist or pharmacist with this document.

Indications/effects.

○ Analgesia for headaches, menstrual cramps, toothache, pain after tooth extraction, sore throat, back pain, joint pain, neuralgia, muscular pain, stiff shoulder pain, ear pain, bruise pain, fracture pain, sprain pain and trauma pain.
○● Antipyretic in case of chills and fever.

Dosage and administration

Take the following doses with water or hot water.
Age - Dose - Number of doses per day
Adults (15 years and older) - 1 tablet - up to 2 doses. When symptoms appear, take on an empty stomach if possible. However, if symptoms reappear, a third dose can be taken.
Allow at least 4 hours between doses.

Under 15 years - Do not take.

< 用法・用量に関連する注意 >
(1) Adhere strictly to the dosage and administration.
(2) To remove tablets: press hard with fingertips on the convex part of the PTP sheet containing the tablets to tear the aluminium foil on the reverse side, remove and take the tablets.
(If accidentally swallowed as it is, it can lead to unexpected accidents such as penetration of the oesophageal mucosa.)

Ingredients/amounts

The product is in the form of very light red, uncoated tablets and contains the following ingredients in each tablet
Ingredients - Amounts - Functions
Loxoprofen sodium hydrate (60 mg as anhydrous) - 68.1 mg.
... Subdues the source of inflammation and pain [prostaglandins].

Additives: hydroxypropyl cellulose, Mg stearate, lactose hydrate, iron sesquioxide.

< 成分・分量に関連する注意 >
Some tablets may show red spots due to additives.

Storage and handling instructions

(1) Store in a cool, dry place out of direct sunlight.
(2) Keep out of reach of children.
(3) Do not replace the product in other containers. (This may cause misuse or change the quality.)
(4) Do not use products after the indicated expiry date.

Contact details.

For enquiries about this product, please contact the shop where you bought it or the following
Customer Relations Office, Daiichi Sankyo Healthcare Co.
3-14-10, Nihonbashi, Chuo-ku, Tokyo 103-8234, Japan
Phone 0120-337-336.
Reception hours 9:00~17:00 (except Saturdays, Sundays and public holidays)